About Omeros

To develop elegant solutions to complex problems, collaborative innovation is a necessity that we foster and celebrate. It’s not just part of the Omeros culture, it’s part of our fabric.

Who Is Omeros?

True innovation requires the right people, and that’s what we have at Omeros – smart, hard-working and creative individuals who collaborate and drive to achieve what has not yet been done. We see strength in diversity – diversity in thought, expertise and experience.

We have taken a similar approach in structuring our company. While many biotechs pursue a single therapeutic area or scientific platform, we are strategically building a deep and diverse pipeline of first-in-class small-molecule and antibody therapeutics. The strength of our scientific discoveries and exclusive intellectual property positions enable our pipeline programs to target highly promising receptors and enzymes that others have not been able to develop.

Although cutting across a wide and diverse range of disorders and therapeutic indications – some orphan, others large-market and many for which there are no approved treatments – all of our drugs in development target critical unmet needs to improve the lives of patients in meaningful ways.

Omeros areas of research

Omeros at a Glance

Omeros - founded in 1994

Founded in 1994

Omeros - based in Seattle, Washington

Based in Seattle, WA on Elliott Bay in Lower Queen Anne

Omeros has multiple early- and late-stage therapeutics in development

Number of employees: Over 200

Omeros has more than 250 employees

Fully vertically integrated with multiple late- and early-stage assets

OMER - publicly traded on NASDAQ

Publicly traded on NASDAQ (OMER)

Company Milestones

Omeros is awarded $6.69 million by NIDA to develop and assess the proprietary PDE7 inhibitor OMS527 in patients with cocaine use disorder
Initiated dosing in Phase 1 clinical trial with OMS1029, Omeros' long-acting MASP-2 inhibitor
OMS906 receives Orphan Drug designation from FDA for treatment of paroxysmal nocturnal hemoglobinuria
Omeros completes OMS906 single-ascending-dose study in healthy subjects with a favorable safety, tolerability, and pharmacokinetic/pharmacodynamic profile
Data demonstrating lectin pathway hyperactivation drives hypocomplementemia and secondary infection in severe acute COVID-19 published in Clinical and Translational Medicine and Frontiers in Immunology
Pivotal clinical trial results for narsoplimab in TA-TMA published in Journal of Clinical Oncology
Omeros sells OMIDRIA® to Rayner Surgical in a transaction valued in excess of $1 billion
Preliminary results announced for OMS906 Phase 1 clinical trial in healthy subjects demonstrating a favorable safety, tolerability, and pharmacokinetic/pharmacodynamic profile
Data demonstrating PDE7 inhibition attenuates nicotine self-administration published in The Journal of Neuroscience
FDA accepts narsoplimab Biologics License Application in TA-TMA for priority review
Omeros reports narsoplimab safety and efficacy data in TA-TMA
MASP-3 inhibitor OMS906 begins clinical trials
Omeros completes a $325 million financing transaction led by Bank of America and J.P. Morgan
Narsoplimab expanded-access program initiates
Omeros discovers new cancer-immunity pathways controlled by GPR174
Omeros scientists win Prix Galien Canada Research Award
Narsoplimab receives Breakthrough Therapy and Orphan Drug designations from FDA for TA-TMA
Narsoplimab receives Orphan Medicinal Product designation for TA-TMA and for IgA nephropathy from the EMA
PDE7 inhibitor OMS527 begins clinical trials
Narsoplimab receives Breakthrough Therapy designation from the FDA for treatment of IgA nephropathy
Narsoplimab receives Orphan Drug designation from the FDA for treatment of IgA nephropathy
Narsoplimab receives Fast Track designation from the FDA for treatment of aHUS
OMIDRIA® (phenylephrine and ketorolac intraocular solution) 1%/0.3% receives FDA approval
Omeros moves to new waterfront headquarters
Omeros enters funding agreements for our GPCR discovery program with Vulcan Inc. and Washington State Life Science Discovery Fund
Omeros establishes a charitable entity to fund nonprofit life sciences organizations in Washington State from GPCR proceeds
Omeros completes IPO
Omeros acquires nura
Omeros is founded